TUESDAY, January 26, 2021 (HealthDay News) – Hospitalizations for diabetes-related foot ulcers (DFU) are increasing, according to a study published online Jan.13 in Diabetes Care.
Emma J. Hamilton, Ph.D., of the University of Western Australia in Perth, and colleagues used data from the Fremantle Diabetes Study phase I (FDS1; 1,296 participants, recruited 1993 to 1996) and II (FDS2; 1,509 participants, recruited 2008 to 2011). Participants were followed from admission to first admission for or with DFU, death, or five years.
The investigators found that the incidence of DFU hospitalizations was 1.9 per 1,000 person years in FDS1 and 4.5 per 1,000 person years in FDS2. The crude incidence rate ratio was 2.40, and the difference in incidence rate was 2.6 per 1,000 person years. FDS2 participants aged 31 to 40 years had the highest incidence rates for all age groups (23.6 per 1,000 person years). Independent predictors of hospitalization for or with DFU include age at diagnosis of diabetes (reversed), hemoglobin A1c, insulin use, height, ln (urinary albumin / creatinine), absence of a leg pulse, previous peripheral revascularization, and peripheral sensory neuropathy ( PSN).
“The incidence of DFU hospitalization complicating type 2 diabetes increased between the FDS phases, especially in the younger participants, and was more likely in those with PSN, peripheral artery disease, and baseline suboptimal glycemic control,” write the authors.
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