Covid-19 in the US: Hydroxychloroquine treatment for Covid-19 is associated with a greater risk of death, the study found | Instant News


The researchers looked at data from more than 96,000 Covid-19 patients from 671 hospitals. All were hospitalized from late December to mid-April and had died or were discharged on April 21. Just under 15,000 are treated with chloroquine or chloroquine hydroxy antimalarials, or one drug combined with antibiotics.

The treatment was associated with a higher risk of death in hospital, the study found. About 1 in 6 patients treated with chloroquine or hydroxychloroquine alone died in the hospital, compared with 1 in 11 patients in the control group.

About 1 in 5 patients treated with chloroquine and antibiotics died and almost 1 in 4 patients treated with hydroxychloroquine and antibiotics died.

“Previous small-scale studies have failed to identify compelling evidence about the benefits and larger, randomized controlled trials have not yet been completed,” Dr. Frank Ruschitzka, director of the Heart Center at Zurich University Hospital and study co-author, said in a statement. .

“However,” he said, “we now know from our research that the possibility that these drugs increase yields on Covid-19 is quite low.”

President Donald Trump has repeatedly heralded hydroxychloroquine as a potential coronavirus drug. Earlier this week he claimed to take a daily dose as prophylaxis to prevent infection.

There are no published studies on the use of antimalarial drugs to prevent Covid-19.

“A few weeks ago, I started taking it,” Trump said. He said he started taking it after consulting a White House doctor, although he did not say his doctor actually recommended the drug.

In addition, this study found serious cardiac arrhythmias were more common among patients who received one of four treatments. The greatest improvement was among the group treated with hydroxychloroquine and antibiotics – 8% of patients developed cardiac arrythmia, compared with 0.3% of the control group.

More than 1.5 million people in the United States tested positive for coronavirus and nearly 95,000 died, according to Johns Hopkins University.

Experts describe the changes the school will make when they are reopened

When students finally return to school, major changes will be in place for help stop the spread of coronavirus.

Items such as masks and hand sanitizers will be a common sight in doll backpacks. Classes and school buses will have fewer people while some office meetings will be conducted by video conferencing, experts say.

At least 4 countries combine numbers from two tests, giving a false picture of the spread of the corona virus
Schools must prevent viruses from entering the campus, and that means health checks, temperature checks, surprising arrivals and limiting campus visitors, Asked Altmann, a spokesman for the American Academy of Pediatrics, said in CNN Coronavirus town hall, Thursday night.

Children with underlying health conditions are very vulnerable, and it is very important that people follow the rules to keep everyone safe, Altmann said. He shares other things that US schools must handle before opening their doors.

Reducing person-to-person transmission at school will be a priority, and educators must prepare smaller classrooms, cover areas that are normally touched, ensure constant hand washing and disinfecting, and avoid sharing supplies, he said.

When students are sick, they must be expelled from school immediately.

“We need to quickly test it, diagnose, isolate and then trace it, which is much easier when there are fewer children they have contacted throughout the day,” Altmann added.

Experts also expressed concern about the impact of the pandemic on children’s mental health.

“We will have a mental health epidemic among our children in this country,” Geoffrey Canada, president of the Harlem Children’s Zone, said during the town hall. “… The poorest children, they know the dead, they know the sick. The air you breathe, the people you pass on the road are suddenly dangerous for you. All the trauma will happen to you our schools and to our classrooms, and we really need to prepare for this, ”

The US epidemic is far from over, scientists say

With only a small proportion of Americans reported being infected, this epidemic is far from over in the United States, according to a team of disease modelers at Imperial College London in England.

Even in the worst affected countries, less than a quarter of the population has been infected, they wrote in a report, posted on the university’s website.

In New York, 16.6% of people were infected, compared with 1% in California, the researchers said.

“Our estimates show that the epidemic is out of control in most of the US,” they wrote. “We estimate that deaths over the next two months can exceed current cumulative deaths more than double.”

CDC issued a new guide about symptoms

About a third of coronavirus infections have no symptoms, the Centers for Disease Control and Prevention in the new guidelines.

It said “the best estimate” is that 0.4% of people who show symptoms and have Covid-19 will die. And an estimated 40% of corona virus transmission occurs before people feel sick.

In the most severe scenarios, the CDC assumes that 1% of people overall with Covid-19 and their symptoms will die. In the most severe scenario, this puts that number at 0.2%.

The CDC estimates that 35% of coronavirus patients have no symptoms

This guide is intended for modelers and public health officials. The CDC notes that the numbers can change when learning more about Covid-19, saying they do not “reflect the impact of changes in behavior, social distance or other interventions.”

The new figures are based on real data received before April 29, he said. This characterizes the figures as an initial estimate from federal agencies.

Several countries reopened before Commemoration Day

Country leading infectious disease experts urge people don’t stay hiding at home during Memorial Day weekend.

“We will have people who want to go there and get some air, said Dr. Anthony Fauci at the global coronavirus city hall.” You can do it. We don’t tell people to just lock up unless you are in a situation where you have a big outbreak that is happening, we don’t have too much of it now in this country. “

But that does not mean throwing wind.

“Go, wear a mask, stay away from six feet from anyone so you have physical distance,” he said. “Go running. Go for a walk. Go fishing. As long as you are not in the crowd and you are not in a situation where you can physically transmit the virus.”

The 50 states have now taken steps to ease the restrictions they place on businesses and services – but urged people to practice social distance and wear masks.

On Friday, North Carolina will allow restaurants to open their dining rooms by far rules. Barber shops and salons can also be opened with limitations.

Alaska allowing all businesses to be reopened, as well as houses of worship, libraries, museums and sports activities, starting at 8 in the morning. Alaska has the fewest cases from all states and have reported one new single digit case since mid-April.

Iowa Governor Kim Reynolds intends to allow cinemas, zoos, aquariums, museums and wedding venues to reopen on Friday. The swimming pool will be allowed to be open for laps and lessons. The bar can be reopened on May 28, and school-sponsored activities, such as sports, can continue on June 1, he said.

Indiana also plans to move forward by opening its large economic plot on Friday, but with restrictions such as limiting social gatherings to 100 people and dining rooms to 50% capacity, and eliminating contact games from the list of sports that are allowed to continue.

But many cities remain under orders to stay at home. In Baltimore, gatherings of more than 10 people were still banned Retail stores remain closed.

Will Brown, Eric Levenson, Maggie Fox from CNN, Anneken Tappe, Gregory Lemos, Ed Lavandera, Ashley Killough and Jen Christensen contributed to this report.

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