Tag Archives: address

Viral-fighting antibodies persist in New Zealand’s Covid-19 patients | Instant News

Viral-fighting antibodies have been found in Kiwi Covid-19 patients for up to eight months after they were infected – a finding that could bode well for the upcoming vaccine rollout.

The new research, released before peer review, has also proven to be of global importance, given that antibodies persist even when no viruses are circulating in the community.

The study analyzed antibodies in a group of 112 New Zealand patients previously infected with the SARS-CoV-2 virus, most of whom had mild symptoms.

Antibodies play an important role in the immune system against pathogens such as the coronavirus.

Once a new virus is recognized, antibodies are specially crafted to bind to the “spike protein” and stop it from entering our cells – while signaling other parts of the immune system to destroy foreign invaders.

“Because antibodies are very specific for an invading pathogen or virus, they also provide a way to track and study a person’s history of infection,” said Dr. Nikki Moreland, an immunologist and biomedical scientist at the University of Auckland.

“In other words, by taking a blood sample of someone, and seeing if there are specific antibodies for SARS-CoV-2 in circulation, it’s possible to determine if they have previously had Covid-19.”

This is useful for diagnosis – especially when the swab has no more virus due to infection several weeks or months ago.

“By studying the level and function of circulating antibodies, it is also possible to determine whether a person has the types of antibodies that might provide protection if they encounter certain viruses or pathogens again.”

The new collaborative study, carried out by PhD student Alana Whitcombe and research scientist Dr Reuben McGregor on the Moreland team, investigates not only the quantity of antibodies in previously infected people – but also their quality.

“Specifically, do people have antibodies that bind to viral spike proteins, can these antibodies neutralize the virus, and how long do these antibodies last?” McGregor said.

In the laboratory, the researchers measured levels of circulating antibodies that bind to spike proteins, as well as whether those antibodies neutralized.

“Since we had samples from people who were infected months earlier, we can use this measurement to see how long the antibodies last.”

Antibodies play an important role in the immune system against pathogens such as the coronavirus.  Photo / 123RF
Antibodies play an important role in the immune system against pathogens such as the coronavirus. Photo / 123RF

“The good news is we observed that the majority of people have neutralizing antibodies that bind to the spike protein and they can be detected for up to eight months after infection.”

While overseas research shows this too, the main difference is that this effect has been demonstrated in countries where Covid-19 has been successfully eliminated.

“People in New Zealand are not re-exposed to the virus like they are in countries with high community transmission rates,” Moreland said.

When someone is re-exposed, he explained, their immune system boosts, which can affect levels of circulating antibodies.

That makes similar data from abroad more difficult to interpret, given it’s unclear whether antibodies were there simply as a result of re-exposure.

“In New Zealand we are fortunate not to have that problem to consider when looking at our data,” said Moreland.

“We believe the antibodies we measured came from the initial infection, so seeing these antibodies last up to eight months was really encouraging.”

What does the vaccine launch mean?

Moreland said the study offers some “positive signals”, given the data from vaccine trials showing the agent induces similar – and in some cases higher – levels of neutralizing antibodies for natural infections.

“So the protection from the vaccine is also likely to last for months and maybe even longer,” he said.

“But we are still studying in real-time, every month we see that the antibodies last one month longer.

“Also, there are several different vaccines and it is important to track the antibody response to different vaccines to measure whether there is a difference in the quality and quantity of the antibodies they produce, and how long the neutralizing antibodies to vaccines last.”

Further studies showed that scientists could accurately measure spike antibodies from finger prick blood samples.

“This could drastically improve the feasibility of large-scale studies to track vaccine antibody responses.” Whitcombe said.

The paper, uploaded to medRxiv’s pre-print server, involved doctors and scientists from the University of Otago, New Zealand Blood Service, Te Punaha Matatini, Callaghan Innovations, the Maurice Wilkins Center, Southern Community Laboratory and the City of Auckland, Starship and Kidz First Children’s Hospital .

“This work would not have been possible without a national network of doctors, nurses, researchers and scientists and highlighted the collaborative nature of New Zealand’s science during the pandemic,” said Moreland.


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Promises were made to address taxpayer problems | Instant News

PESHAWAR: Head of Regional Commissioner for the Regional Tax Office (FBR) Peshawar, Sardar Ali Khawja, said the taxpayer’s problems and complaints would be resolved.

This was expressed when he spoke at an online public forum held at the DGT Regional Office where other relevant officials were also present.

The senior official said effective efforts were being made to solve the real problems of taxpayers. He said a regular public forum was held monthly under Prime Minister Imran Khan’s special direction for the purpose.

He said such forums help ensure better coordination and trust building between taxpayers and tax collection organizations.

From the results of direct contact, the Head of the Regional Tax Office said that the problems of taxpayers related to refunds, NTN and other related problems had mostly been resolved.

The senior official said that timely tax payments were essential to strengthen the country’s economy.

He said cooperation between the merchant community and chambers was needed to expand the tax net, adding taxpayers had to pay taxes on time to avoid fines and other disciplinary action.

A large number of

The public takes part in forums where the main commissioner listens to complaints from taxpayers and issues directions to resolve them.


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Aboriginal names have a proud place in the Australian address | Instant News

(Thomson Reuters Foundation) – The Australia Post has supported a months-long campaign to add Aboriginal place names to addresses to recognize the country’s indigenous people and the traditional names of their lands.

Rachael McPhail, an Aboriginal woman, started a social media campaign in August to ask Australia Post to add traditional place names to postal addresses. He also started an online petition that received about 15,000 signatures.

“Every area on the continent that is now known as Australia has an original place name,” McPhail said in his petition.

“I am calling for place names to be part of the official address information in Australia, the same as postal codes and street names,” said McPhail, who started his campaign by posting photos of his letter with an Aboriginal name.

This week, the Australia Post updated its guidelines for sending and receiving mail, with a section on traditional place names “to recognize traditional custodians of land”.

Australia Post has “a long history of promoting and celebrating indigenous cultures and implementing measures that contribute to lasting reconciliation between Indigenous Australians and non-indigenous Australians”, a spokesman said on Thursday.

A visual example on the Australia Post website features the name McPhail and the traditional name Wiradjuri Country, for the territory in New South Wales where he lives.

Australia’s Aborigines were sacked when the continent was colonized by the British in the 18th century.

The country’s roughly 700,000 indigenous people track near the bottom in nearly every economic and social indicator.

Indigenous activists have long called for native land rights to be recognized, and return to names given by traditional landowners who can trace their lineage back 60,000 years, not those given by white settlers.

As protests over racial inequality swept across many parts of the world earlier this year, Australia saw a renewed push to rename buildings and places.

“It’s a way of acknowledging traditional owners and their ancestors, and recognizing that all these places have names that have been replaced by English names,” said Marcia Langton, a professor of indigenous studies at the University of Melbourne.

“I don’t see a reason why a place can’t have two names. This is happening all over the world as people break free from colonial heritage, ”he said, pointing to Mumbai which was formerly Bombay, and Beijing which was then Peking.

The push to restore original place names has worked in neighboring New Zealand, where many Maori place names have been restored, with other places having two names.

Earlier this year, companies including telecommunications company Vodafone pledged to use the country’s real name Aotearoa more frequently in their operations.

The Australia Post’s move “is an important first step towards decolonization”, said McPhail.

In a social media post, he said he would now lobby the Australia Post to consult with indigenous elders to create a “comprehensive database recording real place names before colonialism”.

Reporting by Rina Chandran @rinachandran; Edited by Michael Taylor. Please appreciate the Thomson Reuters Foundation, the Thomson Reuters charity, covering the lives of people around the world who struggle to live free or fair. Visit news.trust.org


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PM Imran Khan virtually addressing the SCO summit on November 10: source | Instant News

ISLAMABAD / MOSCOW: Prime Minister Imran Khan will virtually address the upcoming Shanghai Cooperation Organization (SCO) Council of Heads of State meeting hosted by Russia on November 10 as a video conference, citing sources, ARY News reported on Thursday.

Russian President Vladimir Putin invited PM Imran Khan to attend the summit of the Shanghai Cooperation Organization (SCO) Council of Heads of State, sources told ARY News.

The prime minister will attend the summit hosted by Russia on November 10, meanwhile, Chinese President Xi Jinping, Indian Prime Minister Narendra and other heads of member states will also participate in the upcoming SCO meeting.

Observers from Afghanistan, Belarus, Iran, Mongolia will attend the upcoming summit. Turkey, Sri Lanka, Azerbaijan, Armenia, Cambodia and Nepal will also participate in the event as dialogue partners for SCO.

Shanghai Cooperation Organization 2019. Reuters

Russia is hosting the meeting as a video conference due to the second wave of the coronavirus pandemic. Russia takes the leadership of the SCO in 2019-2020.

The Council of Heads of State for the Shanghai Cooperation Organization (SCO) will discuss important issues including trade cooperation, the global political and socio-economic consequences of the COVID-19 pandemic, peace efforts in Afghanistan and terrorism, the sources said.

Earlier in October, a statement from the previous SCO press service stated that SCO leaders would discuss strengthening and further developing cooperation within the SCO framework, including in the context of the global political and socio-economic consequences of the COVID-19 pandemic. .

Member countries will focus on ways to promote the practical interactions of SCO member countries in politics, security, trade and economy, cultural and humanitarian relations, and political dialogue, especially in the interests of stability in the SCO space. They will also discuss increasing their country’s trade and economic cooperation and coordination in major international venues, “he said.

The Shanghai Cooperation Organization (SCO) is a regional international assembly consisting of Russia, India, China, Kazakhstan, Kyrgyzstan, Pakistan, Tajikistan and Uzbekistan. Mongolia, Iran, Afghanistan and Belarus are observers, while Armenia, Azerbaijan, Cambodia, Nepal, Sri Lanka and Turkey are dialogue partners of SCO.




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PM, CM will discuss the PTI power show in Swat tomorrow | Instant News

MINGORA: Local leaders, Pakistani lawmakers and minister Tehrik-e-Insaf said on Wednesday that tomorrow’s public meeting will prove the party’s historic show of strength against opposition parties in Swat district.

Prime Minister Imran Khan and Chief Minister Khyber Pakhtunkhwa Mahmood Khan and other PTI leaders will address the public meeting to be held here at the Grassy Ground on Friday. PTI division president Fazal Hakim Khan Yousafzai, provincial minister Dr Amjad Ali, Mohibullah Khan, National Assembly member Salimur Rahman, Dr Haider Ali, Junaid Akbar Khan, Humayun Khan and others visited the public meeting place and reviewed security arrangements for party power shows. Organizers said that the prime minister and chief minister will also launch the distribution of Sahulat Insaf Health cards at the public meeting. They said that people from all walks of life, especially PTI workers and supporters were very enthusiastic about the show of strength.


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