Tag Archives: breast cancer

Food and breast cancer prevention | Lifestyle | Instant News


Roughly one in eight women in the United States will develop breast cancer during their lifetime – that’s roughly 12% of our population.

While the incidence of breast cancer in men was significantly lower, we should note that they are not immune to the disease.

As a dietitian, I have always promoted a healthier diet and although I do not have a “dietary cure” for breast cancer, I can recommend better options for reducing one’s risk. There is no single food that will prevent you from developing breast cancer, but a healthy and balanced diet consisting of fresh fruits & vegetables, dairy products and low-fat protein, will definitely help.

Some nutritionists have started promoting the benefits of mushrooms and mushroom powder to reduce breast cancer risk. Again, no single food can ward off cancer but the nutrients in mushrooms and powder form are undeniable.

Mushrooms stimulate the immune system, reduce blood pressure for some people, and are even believed to fight disease. Mushroom powder contains a certain amount of beta glucan, which has been shown to activate leukocytes. Leukocytes are involved in fighting foreign substances and diseases, such as white blood cells.

Mushrooms aside for now, I firmly believe that one of the best ways to start your day is with a breakfast parfait, which is a very healthy component. I have provided this version before but during this breast cancer awareness month it is important to emphasize it again.

This breakfast parfait is loaded with antioxidants and omega 3. It will keep you full and keep you going in the morning, but more importantly, it will provide you with the nutrients your body needs to stay healthy.

My recipe calls for blueberries but you can substitute strawberries or blackberries, or use a mixture of the three. Walnuts are most nutritious but replace them occasionally with pumpkin seeds. With this recipe, you will also get the healthy fats that your body needs. Feel free to try it for a week or two – it might even become a daily habit.

BREAKFAST PARFAITS (Serves 1)

1 cup low-fat Greek yogurt (preferably plain)

2/3 cup blueberries (frozen or fresh)

2 tablespoons chopped walnuts

To prepare the parfait, in a bowl, coat about ½ the yogurt and top it with berries. Sprinkle about half the seeds and walnuts.

Repeat layers and serve.

(Candy Work is a certified physician assistant and registered nutritionist. She has been practicing at the Olean Medical Group since 2015.)

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$ 14 million in grant to support Pacific Island cancer research | Instant News


PICTURE: Pacific Island Partnership for Health Equality Leaders at the Program Steering Committee Meeting held in February 2019 at the University of Guam. (From left) Neal A. Palafox, UHCC; Engelberta …
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Credit: University of Guam

The University of Guam and the University of Hawai’i Cancer Center have each been awarded a five-year grant totaling more than $ 14 million to reduce the impact of cancer on the Pacific Islands through cancer research, career training, and community outreach. The collaboration between the two universities, known as the Pacific Island Partnership for Cancer Health Equity (PIPCHE), will be funded by the National Cancer Institute until 31 August 2025.

Funds from PIPCHE are used to support the research infrastructure needed to address significant cancer health disparities in the Pacific.

“PIPCHE has been truly transformational for research here at UOG for this region,” said Rachael Leon Guerrero, Ph.D., RD, principal investigator of the grant and vice-chancellor of research and sponsored programs at the University of Guam. “Prior to PIPCHE, there was very little cancer and health-related research going on that was relevant to the Guam population. Now we have several federal research grants studying cancer, childhood obesity, cardiometabolic health, and dementia.”

PIPCHE is the only NCI-funded Pacific-based partnership addressing cancer disparities in other US-affiliated Hawai’i, Guam and Pacific Island communities, which include the Northern Mariana Islands, American Sāmoa, Federated States of Micronesia, Marshall Islands and Palau . It also provides research training for students and early career scientists while engaging the public in outreach activities to advance knowledge, awareness, behavior change and public health policies in Guam and Hawai’i.

“We are using cancer research as a platform to bring equity and resilience to indigenous Pacific peoples,” said Neal A. Palafox, MD, MPH, UH Cancer Center researcher and principal investigator of the grant at UHCC. “… The investment has brought cancer researchers and scientific leaders native to the Pacific, relevant Pacific-based interventions for addressing cancer disparities, and has increased the capacity for both institutions to understand and achieve cancer health justice in the Pacific.”

The first PIPCHE grant was awarded to the University of Guam and the UH Cancer Center in 2003.Since then, the fund has supported 25 research projects, trained more than 100 underrepresented students and early career scientists, contributed to more than 100 peer-reviewed publications, and , in the last cycle alone, raised more than $ 34 million in additional external funding to explore research questions unique to the Pacific region.

“17 years have been an exciting and eye-opening journey,” said Palafox.

Cancer prevention and control in the Pacific is a joint mission between the UH Cancer Center, the University of Guam, and their collaborators. PIPCHE provides a platform to do more than any agency alone can accomplish.

This partnership effort was directed by Leon Guerrero and Palafox as well as the Dean of the UOG Health Faculty Margaret Hattori-Uchima, Ph.D., RN, and Director of the UH Cancer Center Randall Holcombe, MD, MBA, along with other teams. than 50 investigators and staff at partner institutions.

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Fasting diet, hormonal therapy can help in the treatment of breast cancer: Study – health | Instant News


Fasting-mimicking diet in combination with hormonal therapy has the potential to help in the treatment of breast cancer, according to a USC-led team of international scientists.

In studies on mice and two little breast cancer clinical trials, researchers at the University of southern California and IFOM cancer Institute in Milan, in collaboration with Genoa University — found that starvation-mimicking diet reduces blood insulin, insulin-like growth factor 1 (IGF1) and leptin.

In mice, these effects appear to increase the power of cancer hormonal agents tamoxifen and fulvestrant and delay any resistance. Results of the 36 women who received hormone therapy and a fasting-mimicking diet are promising but researchers say it’s still too early to determine whether the effect is confirmed in large clinical trials.

The study was published in the journal Nature.

“Our new study shows that fasting-mimicking diet with the endocrine therapy of breast cancer has the potential to not only reduce the tumor and reverse the resistant tumors in mice,” says Valter Longo, the study’s co-senior author of the study and Director of the Institute of longevity part of the USC Leonard Davis school of gerontology and Professor of biological Sciences at the USC Dornsife College of letters, arts and Sciences.

“We have data that for the first time suggests that starvation-mimicking diet works by changing at least three different factors: IGF1, leptin and insulin,” added Longo.

The researchers argue that two small clinical trials feasibility studies, which have shown promising results, but they in no way are not final. They believe that the obtained results support further clinical studies fasting-mimicking diet is used in combination with endocrine therapy in hormone-receptor-positive breast cancer.

Scientists have also contributed to a recent clinical study in 129 patients with breast cancer, conducted at the University of Leiden. The results, published last month in nature communications, there increased effectiveness of chemotherapy in patients receiving a combination of chemotherapy and fasting-mimicking diet.

In two new clinical trials, one of which was aimed at the study co-author Alessio Nencioni — patients with hormone-receptor-positive breast cancer receiving treatment with estrogens along with cycles of a fasting-mimicking diet, it seemed, was experiencing metabolic changes, similar to those observed in mice.

These changes included the reduction of insulin, leptin and IGF1 levels, with the last two remaining at a low level over a long period. In mice, these long-term consequences associated with prolonged antitumor activity, therefore further studies are needed on humans.

“Some patients were followed by monthly cycles of a fasting-mimicking diet for almost two years without any problems, suggesting it is well-tolerated intervention. We hope this means that the nutrition program that mimics starvation may one day represent the weapons to better fight cancer patients receiving hormonal therapy without serious side effects,” said Nencioni.

“The results in mice are very promising. And early clinical results show potential, but now we have to see how it works in 300 to 400-patient trial,” explained Longo.

The data also suggest that in mice, fasting-mimicking diet for the prevention of tamoxifen-induced endometrial hyperplasia, a condition in which endometrium (or uterus) becomes abnormally thick. The study’s authors believe that this potential use in fasting diet needs to be examined in more detail, given the prevalence of this side effect of tamoxifen and the limited options for its prevention.

About 80 percent of all breast cancers Express estrogen and/or progesterone. The most common forms of hormonal therapy for breast cancer These work by blocking hormones from attaching to receptors on cancer cells or a decrease in the production of hormones in the body. Endocrine therapy is often effective in these hormone-receptor-positive tumors, but long-term benefits are often hampered by a resistance to treatment.

Several clinical trials, including one at USC on breast cancer and prostate patients, is currently studying the effect of fasting-mimicking diets in combination with various anticancer drugs.

“I like to call it non-toxic substitution cancer treatment. The clinical trial data we’ve just published — along with many fodder studies published over the last 12 years, suggest that cycles of fasting-mimicking diet has the potential to make standard therapy more effective against various types of cancer, each time changing a different factor or nutrients required for cancer cell survival,” said Longo.

(This story was published by wire Agency to feed without changes to the text. Only the title was changed.)

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‘Cheap’ 3P pill from diabetes may be the answer for treatment of the syndrome, doctors say | Instant News


In ‘cheap’ diabetes pills may be the answer for effective treatment coronavirusthe researchers believe.

Metformin, sold as Glucophage, worth about 3P a tablet with some doctors in the Chinese city of Wuhan, where the pandemic began, call it ‘wonder drug’ after studies show that it reduces the inflammatory response of the body.

Inflammation is one of the main causes of death for those with a killer bug from drugs, given to patients with diabetes type 2 diabetes since the 1950-ies, potentially crucial, until a vaccine is developed.

Earlier this month, experts from Wuhan revealed the mortality rate among viral patients taking medications for diabetes were significantly lower than not.

For updates coronavirusfollow our live blog Here.



Scientists in the two studies consider pill can effectively treat coronavirus

The study involved analysis of data from 104 patients receiving Metformin, who were hospitalized with the virus between January and March, and compared with the records of 179 others with the same disease severity.

Three patients receiving Metformin died compared to 22 is not on the drug, with results reflecting a similar study conducted at the University of Minnesota in the United States.

Metformin is already used by the NHS and is also tested as a treatment for heart disease and breast cancer.

Susie Birkett was given the drug in the composition of the court of private treatment in the Oncology clinic in London and believes that to effectively combat her breast cancer.

Speaking at Daily Mailshe said: “This is a very strong medication, but it was slow.

“Who will pay for large trials to regulatory approval, when there is no profit in the end? Metformin very cheap.”

However, researchers also believe a combination of Hydroxychloroquine and chloroquine – emergency approval of America food and drug administration (FDA) for use by people who are in critical condition in the hospital with Covid-19-can be deadly in combination with Metformin.

Two medications commonly used to treat malaria and autoimmune diseases, and that showed promising results in helping to treat certain types of cancer.

But research Ludwig Institute for cancer research and Anirban Maitra as a result, between 30% and 40% dying mice when the drug was combined with Metformin, according to Diabetes.Ko.UK.

There is no vaccine not yet approved for commercial use against Covid-19, but more than a dozen vaccines from more than 100 applicants around the world are being tested on humans.

Recently in China military received a “green light” to use the vaccine developed by its research unit and Cancino biological products after clinical trials proved it was safe and showed some efficacy, the company said on Monday.

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The net field in cancer surgery has become possible thanks to luminous paint: study | Instant News


It is very important when removing a cancerous tumor, to ensure that any small remnants of malignant mass left. Surgeons always aim for a “clean field” when you perform operations on cancer patients.

Leaving the cancerous tissue inside the body can increase the chance of spread of the disease and relapses. Appearance can lead to reduced life expectancy.

To ensure the accuracy of the operation, researchers from the University of Pennsylvania invented a technique to help surgeons in accurately seeing and making sure no diseased tissue is left behind.

The team found that injecting a dye that glows under infrared light, can illuminate cancerous tissue in the primary tumor and affected lymph nodes.

In their study, the researchers performed surgery on dogs to remove breast tumors in the veterinary school hospital Ryan. Breast cancer in dogs are similar to breast cancer in women.

In addition, the research group suggests that by using different dyes the more specific the target cancer cells can improve the consequences for patients, including breast-conserving surgery to treat their disease.

The results of the study were published in the journal BIOCHEMISTRY on 17 June 2020.

See Also: The Laser Can Detect Cancer Cells And Kill Him

That Indocyanine green is used?

In the medical field injection of indocyanine green medical dye used in tests to determine liver function, cardiac output and blood flow in the liver. Dye is injected intravenously.

In addition, it is also used to make certain parts of the eye more visible during medical procedures such as angiography.

In a recent study, researchers from the school of medicine Perelman, in collaboration with David Holt, a veterinarian and the other from the University of Pennsylvania, also used the same FDA-approved contrast agent indocyanine green (ICG).

Dye that glows in infrared light, was used to distinguish normal from cancerous tissue for several years in various types of cancer. Scientists believe that ICG accumulates in cancer because it seeps through the fast-growing blood vessels in tumors.

The aim of this work was to verify the approach in Pet dogs mammary tumors as a model for organ-sparing surgery in women. All pet owners provided consent to participate in the study. On the day before surgery, dogs were given an injection of ICG.

Operations the fangs were either surgery lumpectomy or mastectomy. The procedure went as well as they usually, after the standard of medical care, protocols and procedures. After that the surgeons cut out the tumor is observed with near-infrared light. They also examined the surgical site to look for signs glowing GSI.

The glow of the tumor: prognostic problem for the lymph nodes

The study authors found that large tumor accumulates more dye. In addition, they were also interested in the analysis of the lymph nodes of the dog. According to Holt, they were able to identify and draining lymph nodes and children with metastatic disease.

In modern practice with breast cancer patients, radioisotopes injected into the breast to identify a plum or regional lymph nodes. Using infrared imaging agent intravenously, radioactive substances, and protective shielding will disappear.

Holt noted that the ICG may be administered via injection prior to surgery, the risk of removal of too many lymph nodes or fragments, leaving traces could have been avoided. In addition, in their subsequent work, the team plans to continue studies of the effectiveness of their paint patients people with cancer.

See Also: New evidence about why clear margins in breast cancer surgery, are such good news

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