Tag Archives: effect

The Johnson and Johnson vaccines are investigated for the rare side effects of blood clots | Instant News


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Johnson & Johnson Covid-19 vaccine boxes are stored in the refrigerator at the vaccination site that appears at the Albanian Islamic Cultural Center on Staten Island, New York. Photo / AP

European drug regulators have revealed that they are reviewing rare blood clots suffered by recipients of the Johnson and Johnson vaccine in the United States.

The European Medicines Agency (EMA) said it was investigating four serious cases but it was unclear at this stage whether the clot was related to vaccines or other medical problems.

Three of the cases occurred during the US launch in which nearly five million had been vaccinated by Thursday, while one case occurred during clinical trials.

In one case, the person died from complications.

Dr. Mark Ghaly, Secretary, California Health and Human Services, left, injects California Governor Gavin Newsom, right, at Baldwin Hills Crenshaw Plaza in Los Angeles.  Photo / AP
Dr. Mark Ghaly, Secretary, California Health and Human Services, left, injects California Governor Gavin Newsom, right, at Baldwin Hills Crenshaw Plaza in Los Angeles. Photo / AP

Johnson and Johnson said they were aware of the review and were working with regulators to assess the matter, but insisted “there is no clear causal link between this rare event and the Janssen Covid-19 vaccine”.

The main medicinal injections are currently only available in the US and are scheduled to be published in the European Union in the coming weeks.

New Zealand has ordered up to five million doses of the Janssen vaccine but is still awaiting more data before approval.

Australia has yet to commit to Johnson and Johnson vaccines but complications have come amid concerns with AstraZeneca’s injections, which threaten to destabilize confidence in the launch.

Professor Mary-Louise McLaws, an epidemiologist at the University of New South Wales, insists that the extremely rare complications of any vaccine far outweigh the threat of Covid-19.

“It’s all about placing a proportionate risk of death in our elderly cohort representing 100 percent of all coronavirus deaths in Australia,” he told NCA NewsWire.

People sit in the observation area after being inoculated with the Johnson & Johnson vaccine in Philadelphia.  Photo / AP
People sit in the observation area after being inoculated with the Johnson & Johnson vaccine in Philadelphia. Photo / AP

“They only die if they catch Covid, so to prevent them from getting infected, we have to fence them off.

“In the context of a pandemic, there is a huge risk of death for this older group so you want to protect them by vaccinating everyone, but especially children who are at greater risk of catching and transmitting it.”

Although Australia has yet to commit to a Johnson and Johnson vaccine, a hiccup from this week’s EMA threatens to complicate already-increasing supply problems around the world.

Prime Minister Scott Morrison on Thursday refused to commit to having the nation’s jab launch completed this year because Professor McLaws offers a much bleaker timeline – he expects vaccine supply delays to keep Australia’s borders closed through the end of 2022.

New Zealand has agreed to receive up to 7.6 million doses of AstraZeneca vaccine.

AstraZeneca injections will not be offered to Australians under the age of 50 following the advice of the Australian Technical Advisory Group on Immunization, which will free supplies for the older group.

Northwell Health registered nurses injected members of the Albert Capa mosque with the Johnson & Johnson Covid-19 vaccine.  Photo / AP
Northwell Health registered nurses injected members of the Albert Capa mosque with the Johnson & Johnson Covid-19 vaccine. Photo / AP

“So now we have less people who need AstraZeneca, we have more space (supply),” said the professor.

“But if we want to open in the near future next year, AstraZeneca’s supply must be increased so that people get vaccinated on time because there is a three month delay between the first and second injections.

“So just because there are fewer people who need it doesn’t mean we’re out of the jungle because the government has to deploy two troops and they have to adjust the pace so we can open our borders.”

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Foreign companies are creating more jobs in Switzerland despite the pandemic | Instant News


(MENAFN – Swissinfo) Switzerland remains an attractive location for foreign companies, creating more jobs last year than in 2019 – despite the economic impact of the coronavirus pandemic, Swiss public television SRF and RTS have reported.

This content is published on April 9, 2021 – 09:25 April 9, 2021 – 09:25 SRF / RTS / ilj

Foreign companies accounted for 11% more jobs in 2020, bringing the total to nearly 1,200, even if the total number of companies moving to the country fell (by 9%), said the SRF. Over the next three years, they are expected to drive the creation of 3,500 jobs.

“The workforce is highly qualified, and taxation is lucrative and Switzerland is in the middle of Europe,” said External Links Jim Fitzgerald, director of Tiffin Metal at the SwissExternal link.

The company, which produces specialty metal solutions for various industries, decided to open its first branch outside the US in Schmitten, in the canton of Friborg.

Stability

These figures come at a time of general global economic woes caused by the coronavirus pandemic. The Swiss economy shrank 2.9% last year as a result of Covid-19, the worst annual contraction since the aftermath of the oil crisis in 1975. But officials are optimistic that the Swiss economy will recover.

Patrick Wermelinger, of Swiss Global Enterprise, Switzerland’s export promotion agency, said Switzerland’s stability had played a role.

‘In a year of crisis, stability, long-term planning, economic security play a more important role. This is in Switzerland’s favor. But we were surprised by how many new jobs were being created, ‘he told SRF.

Companies from China, the US and Germany create the most jobs.

Switzerland is also one of the few to have attracted more foreign investment in 2020, according to the SRF. Only Ireland is attracting more, the fDi Markets Financial Times report found.

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UPMC opens a COVID-19 rehabilitation program in Italy | Instant News


the word 9 March.

The Post-COVID-19 Rehabilitation Program follows the UPMC clinical model developed in Pittsburgh. This will give patients at the UPMC Institute for Health Chianciano Terme in the Tuscany region access to cardiologists, physical therapists, pneumologists, nutritionists and psychologists. The professionals will treat the motor, respiratory, metabolic and neurological conditions associated with COVID-19.

How long patients stay in the program will vary depending on the severity of their post-COVID-19 symptoms, the UPMC said.

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Switzerland – The pandemic puts Geneva Airport in the red for the first time | Instant News


(MENAFN – Swissinfo) Geneva Airport recorded a loss of CHF129.5 million ($ 145 million) in 2020, due to the effects of the coronavirus pandemic.

This content will be published on 16 February 2021 – 16:00 16 February 2021 – 16:00 RTS / jc

This compares to a gain of CHF84.1 million in 2019, the airport said on Tuesday.

This loss is the first in its history, due to a decline in the number of passengers due to restrictions on international travel. In 2020, more than 5 million passengers boarded or disembarked at Geneva airports, which is 69% less than in 2019.

The number of takeoffs and landings has also fallen sharply. Overall this year, 86,353 aircraft movements were recorded, down 54 percent over the previous year.

Cutting costs and losing jobs

To cushion the shock as much as possible, Geneva Airport said it had postponed dozens of projects and also turned the cost screw. After a record CHF250 million the previous year, investment was reduced to just under CHF135 million, while personnel costs were cut by 12% and operating costs by 40%.

Airports are benefiting from short-term employment subsidies, but still have to cut around 30 full-time jobs compared to late 2019.

“Our task today is to avoid any harm to the airport’s future,” Geneva Airport Director André Schneider told Swiss public broadcaster RTS on Tuesday. “We are ready to take the necessary action, as we did last year, when we can cut costs massively. But on the other hand, if traffic continues, we have to make sure we have the staff and infrastructure to be able to handle it. ‘

Schneider said he expects air traffic to increase again by 2024 to “allow us to rebuild our losses and return to pre-crisis financial health for the next ten years”.

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Mild side effects from the COVID-19 vaccine are normal | Instant News


KARACHI: Certain reactions after vaccination of redness, swelling or pain around the injection site are normal. Fatigue, fever, headaches, and pain in the limbs were also not uncommon in the first three days after vaccination, the German news agency DW reported. These normal vaccine reactions are usually mild and subside after a few days. They show that the vaccine is working.

Therefore, typical vaccination reactions have also been reported after receiving the BioNTech-Pfizer, Moderna, AstraZeneca and Russia Sputnik V vaccines, which have already been used.

In addition, there are also cases of sometimes severe side effects after vaccination, such as allergic shock. Overall, approved vaccines are safe, according to the European Medicines Agency (EMA), the US Food and Drug Administration (FDA) and the World Health Organization (WHO).

Some of the newer vaccines – the so-called mRNA vaccines, only contain blueprints for components of the COVID-19 pathogen. The other is called a vector vaccine that uses a harmless adenovirus as a transporter to introduce the SARS-CoV-2 surface protein, a spike protein, and thereby trigger an immune response.

According to German DW, three vaccines are being developed in China. Those are the vaccines from the Sinovac Biotech vaccine company called CoronaVac, Sinopharm’s Vero vaccine and CanSino Biologics called Ad5-nCoV or Convidecia.

Only partial data on vaccine efficacy have been released from phase II and III trials, respectively. Sinopharm is the first company to officially announce data at the turn of 2020.

The situation also remains unclear with regard to vaccine approval. More than one million people have been vaccinated with the Sinopharm vaccine, but this is being done as part of a study or with emergency approval.

The Sinopharm vaccine called Vero is based on an inactive virus. Phase III trials for Vero have been conducted in 10 countries around the world, including the United Arab Emirates, Bahrain, Peru, Morocco, Argentina, Jordan and Pakistan. Phase III trials for Vero have been conducted in 10 countries around the world, including the United Arab Emirates, Bahrain, Peru, Morocco, Argentina, Jordan and Pakistan. Quoting a Chinese doctor, Britain’s Daily Mail, claims that Sinopharm’s Chinese Covid-19 vaccine is considered the least safe because of its 73 side effects. Some of the side effects include blindness, high blood pressure and loss of taste and urinary problems. This was reported in a blog published on the Chinese microblog website Weibo, but has since been removed from the site. It was also reproduced by Taiwan News, Apple Daily and Vice of America. Chinese doctors dubbed the information misleading and baseless because of the unnecessary hype.

The BioNTech-Pfizer vaccine is produced jointly by Germany and the US, the BNT162b2 vaccine. Typical vaccination reactions such as fatigue and headache are less frequent and weaker in older patients. However, because this mRNA vaccine has been used, some patients experience severe allergic reactions immediately after injection. One patient in the US and two in the UK even experienced anaphylactic shock, associated with redness of the skin and shortness of breath.

Because these people have no previous illness or are not known to be allergic to certain vaccine ingredients, the UK Medicines and Health Products Regulatory Agency (MHRA) warns certain people who are allergic to certain vaccine ingredients, or have suffered from anaphylactic shock. , against vaccination. The manufacturer saw no direct link to vaccination in the case of a doctor in the US with no previous illness who died from brain hemorrhage due to immune thrombocytopenia 16 days after receiving the vaccination. This occurs when the immune system reduces the platelet count.

The headlines were made when 33 people in Norway died within days of the first vaccination, all of whom were over 75 years old and suffering from severe underlying illness.

According to King’s College London, 37 percent of those who received the Pfizer vaccine in January experienced some pain and swelling at the puncture site. 14 percent of people who received the first dose reported fever, chills and body aches that went away within days. All trial and experience confirms the vaccine is safe and efficacious. However, vaccinated people must continue to observe social distancing as nothing provides 100 percent security against Covid-19. Doctors recommend using paracetamol to treat abrasions and scars on the upper arms after vaccination. Some experts are of the view that if fever and other symptoms appear after the Covid 19 test is mandatory.

According to CNN, certain side effects of the vaccine will go away within a day or two. However some people may or may not report any side effects. In the case of those who do not experience side effects, that does not mean that the vaccine is not working. In most cases, side effects have been reported after the second dose. According to CNBC, a high level of fever that lasts for two days could be an indication that Covid-19 is mandatory for testing. This underlines contacting a doctor to ascertain the cause if any of the symptoms persist for more than two days.

Another vaccine mRNA-1273, from the US company Moderna is also a gene-based vaccine.

During clinical trials, participants tolerated the vaccine well, according to manufacturers and testing authorities. The usual vaccination reactions are mild or moderate and do not last long. However, nearly 10% of those vaccinated with mRNA-1273 experienced fatigue, according to an interim report by an independent surveillance panel.

A severe allergic reaction to the Moderna vaccine is “rare,” according to the US Centers for Disease Control and Prevention (CDC). The CDC based this assessment on documenting 4,041,396 doses of vaccine administered between 21 December 2020 and 10 January 2021. A total of 108 allergic reactions were recorded, but only 10 recipients developed anaphylactic shock. The CDC reports that no allergic reactions resulted in death.

Very few people who receive the Moderna vaccine develop facial nerve paralysis. It is possible that the side effects are not triggered by the mRNA, but by the lipid nanoparticles which function as carriers for mRNA and are then broken down by the body.

Isolated cases of facial paralysis, mostly transient, occur sporadically during clinical trials of the BioNTech / Pfizer and Moderna vaccines, but also during the ongoing vaccinations in Israel.

In the case of the Anglo-Swedish company AstraZeneca, an incident during a clinical trial in September caused an uproar because one person developed inflammation of the spinal cord after vaccination. The trial was paused briefly until an independent panel of experts determined that the inflammation might not be related to vaccination. In contrast, only typical vaccination reactions occur with vaccines from AstraZeneca. Again, vaccine reactions are less frequent and mild in the elderly. This is a vector vaccine.

In Russia, as early as August 2020, the Gam-COVID-Vac (Sputnik V) vector vaccine has been approved, but without waiting for phase III trials involving tens of thousands of subjects. Sputnik V uses two different modified adenoviruses (rAd26-S and rAd5-S). However, Sputnik V is already in use in addition to Russia in many other countries, including Belarus, UAE, India, Brazil and Argentina. In Argentina, typical vaccination reactions occurred in 317 out of a total of 32,013 people vaccinated, according to the Argentine Ministry of Health. There have been no reports of severe side effects after Sputnik V vaccination.

All the risks and side effects recorded so far are just a snapshot of the last few months – these should be noted despite all the excitement about the rapid development of a vaccine. Nothing is known yet about the possible long-term effects of each vaccine. Only the long-term studies accompanying vaccinations around the world and will continue since approval will provide clarity.

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