- Scientists have developed a new system that uses the CRISPR genome editing system to attack and kill cancer cells.
- The goal of this system is to eliminate cells directly, just like “scissors”, cutting their DNA and killing them.
- Additional trials and tests are needed, but promising new systems can eventually be used to fight cancer in humans.
Since human doctors realized that this is fatal, the fight against cancer has been ongoing. Although it always seems to be out of reach with real treatments, many advances have been made in the fight against the disease. Researchers at Tel Aviv University believe that with the help of the CRISPR genome editing system, they are moving towards this incredible goal.
As the scientist published in Scientific progress, The tool was developed to correct potentially harmful genetic quirks, and may prove to be the ultimate tool to eradicate deadly cancer. The team’s research shows that by using what they call a “new lipid nanoparticle-based delivery system,” they can specifically target cancer cells and effectively kill them without the opportunity to reactivate them.
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The description of how this system attacks cancer cells sounds absolutely incredible. Scientists use nanoparticles to send messages to the CRISPR enzyme Cas9 to target cancer cells and “act as molecular scissors” to slice the cell’s DNA and kill it.
Researchers are trying to prove that the system can work by targeting glioblastoma and metastatic ovarian cancer, the two cancers with the highest mortality rates. As we all know, they are aggressive cancers that kill many people every year. When targeting these cancers in mice, a single treatment with the new CRISPR system can double the animal’s survival rate. It was after just one round of treatment, which is very incredible.
Professor Dan Peer, the co-author of the study, said: “This is the first study in the world to prove that the CRISPR genome editing system can be used to effectively treat cancer in living animals.” Said in the statement. “It must be emphasized that this is not chemotherapy. There are no side effects, and cancer cells treated with this method will never be active again. Cas9 molecular scissors cut the cancer cell’s DNA, thereby neutralizing and permanently preventing replication.”
Looking to the future, researchers hope to try to solve other kinds of diseases, including blood cancer and genetic diseases, to understand how much the gene editing system can make. If the test proves to be promising, we may soon see that CRISPR can be used for a variety of diseases, and even as a promising tool to eliminate many types of cancer.