Tag Archives: medical conditions

This is a good line for queuing haters when it comes to shopping for food and vaccines | Instant News


Philadelphia city employees lined up to schedule their second Covid-19 vaccine shot last week. Our columnist is not among them.

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What you can and cannot do if you have been vaccinated: travel, gatherings, risk factors, what you need to know | Instant News



Many people are hoping that getting a Covid-19 vaccine will mark an immediate return to normal: more masks, more distancing, safe dining and big hugs with friends. The reality is more complicated. For now, people who have been vaccinated must navigate decision-making in a world where the vaccinated and the unvaccinated will coexist for months, even within the same household. So what should and shouldn’t you do? The U.S. Centers for Disease Control and Prevention is expected to issue guidelines soon. “We are taking the time to get it right and will be posting the tips soon,” CDC director Rochelle Walensky said on Friday. “We want to make sure the communication is crystal clear.” In the meantime, other experts are somewhat divided. Some say people who have been vaccinated can and should have a lot more freedom, and think it is important to stress this to encourage more people to get vaccinated. Others are more conservative, saying it is too early to abandon too many precautions without more conclusive data on the effectiveness of vaccines against new variants and the potential risk of vaccinated people spreading the virus to unvaccinated people. Most agree that until we get closer to herd immunity – when a substantial majority of the population is protected by vaccination or natural infection so the virus cannot easily spread – wearing masks , social distancing and avoiding crowded gatherings indoors should be common practice in public spaces. “Particularly during these several months when vaccination coverage is low, we are still learning about the variants, and we still have to know this further transmission, the public health message is really to maintain these behaviors,” explains Chris Beyrer, professor. of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. “Until we get out of it. We’re not out of it yet. A doctor shows his vaccination record. Photo: chandan khanna / Agence France-Presse / Getty Images Here are the scientists’ recommendations on how to assess risks. Can vaccinated people meet other vaccinated people? Most experts agree that once fully vaccinated – two weeks after your second dose of Pfizer or Moderna vaccine or about a month after the Johnson & Johnson vaccine – it is safe to meet other fully vaccinated people inside without. mask or distance. But gatherings should be small. Getting together with other vaccinated people is “scientifically very safe,” says Paul E. Sax, clinical director of the division of infectious diseases at Brigham and Women’s Hospital in Boston. Nothing is 100% effective, but “getting together with other vaccinated people is very close,” he says. “I don’t think people should run into a crowded bar where people are yelling at each other,” he says. “But the kind of socializing that is part of human nature and that has been suspended for a lot of people – it can resume.” The larger the group, the more risky the interaction, because you can’t verify that everyone is vaccinated and you don’t know what their exposures are, says Leana Wen, emergency physician and professor of public health at the University. George Washington in Washington, DC. “I’m talking about another couple or maybe two other couples at most,” says Dr. Wen. Monica Gandhi, an infectious disease physician and professor of medicine at the University of California, San Francisco, is less conservative, saying people who have been vaccinated should feel more comfortable. “They can organize dinners. They can go to a restaurant. They can go to the movies, ”she said. But she notes that even those vaccinated will have to adhere to mask and distance requirements in these public places until we achieve herd immunity. What if adults are vaccinated but children are not? There is currently no licensed vaccine for children and adolescents under the age of 16. “This will be one of those issues that families will have to grapple with and exercise caution with,” says Dr Beyrer. There is a significant difference between young children and adolescents or adolescents in terms of transmitting the virus and getting the disease, says Dr. Sax. Adolescents catch and transmit Covid-19 in the same way as young adults, while young children do not contract the symptomatic disease as often and do not seem to transmit as much. “Each family and group of friends will make decisions based on their own tolerance for risk,” says Dr. Sax. People who are immunocompromised and their families should be more careful because vaccines in general may be less effective in them, says Dr. Sax. Dr. Wen says she recommends families continue to take playtime precautions when adults are vaccinated but children are not. “If these families also team up with other families, it’s a risky scenario that I wouldn’t recommend at this time,” says Dr Wen of indoor gatherings. “They could be an asymptomatic carrier who would then pass it on to their children. And if the kids are in school or daycare, there might be a further gap from that. What is the final question on whether vaccinated people can transmit the virus to unvaccinated people? Recent studies have shown that vaccination reduces asymptomatic infection by more than 80% compared to unvaccinated people and that nasal viral loads are low and potentially non-infectious, says Dr Gandhi. But other experts say the evidence is preliminary and more conclusive evidence is needed. And the new variants raise additional questions about the effectiveness of vaccines. What activities should I prioritize after being vaccinated? Schedule any routine medical and health appointments you’ve postponed, says Dr. Wen. Get your colonoscopy, mammogram, or dental cleaning. Plan elective surgery. “Anything like that, you should take it back because you’re well protected,” says Dr Wen. What about travel? Once you’re vaccinated, traveling itself is less risky, says Dr Wen, as is staying in hotels or going to restaurants, as long as you follow safety protocols. But be careful about how you meet people once you get to your destination, she says, especially if they aren’t vaccinated or if they live in an area with high transmission rates. Is it safe for my elderly parents to travel for a visit? If the grandparents are now fully vaccinated, they should be able to travel safely for a visit. “The trip itself is very low risk,” says Dr. Wen. “If they follow precautions like wearing a mask, the risk of them contracting the coronavirus and passing it on to the rest of the family is extremely low and the payoff is huge. People can’t wait to see their families. But always weigh the specifics of your situation. If you have an older unvaccinated teenager and an elderly, frail grandparent, consider more precautions, says Gregory Poland, director of the Mayo Vaccine Research Group in Rochester, Minnesota. Which activities have a lower and higher risk, even after vaccination? People who have been vaccinated may feel comfortable performing quiet indoor activities where people usually need to be masked and kept away, such as visiting an infrequently visited museum, says Dr Sax. Outdoor activities are even safer. High-risk situations include indoor restaurants, bars, gyms, and places of worship, where people sing and talk. “We don’t want to push the boundaries of what vaccines can do before the number of cases drops,” says Dr Sax. He and his doctor wife are both fully vaccinated but won’t dine in restaurants until the number of cases and hospitalizations are significantly lower, he says. Airports in Paris and Singapore, along with airlines such as United and JetBlue, are experimenting with apps that verify travelers are not Covid before boarding. The WSJ is heading to an airport in Rome to see how a digital health passport works. Photo credit: AOKpass —Betsy McKay contributed to this article. Write Sumathi Reddy at [email protected] Share your thoughts If you’ve been vaccinated, what are you comfortable doing? Copyright © 2020 Dow Jones & Company, Inc. All rights reserved. 87990cbe856818d5eddac44c7b1cdeb8.



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Brazil’s Covid-19 Variant Inundates Local Hospitals, Attacking Younger Patients | Instant News


SÃO PAULO – Researchers and doctors sound the alarm a new, more aggressive type of coronavirus from the Amazon region of Brazil, which they believe is responsible for the recent increase in deaths, as well as infections in younger people, in parts of South America.

Brazil’s daily death toll from the disease climbed to its highest level this week, pushing the total number of Covid-19 deaths in the country past a quarter of a million. On Tuesday, Brazil reported a record 1,641 deaths from Covid. Neighboring Peru is struggling to curb a second wave of infections.

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The new variant, known as P.1, was 1.4 to 2.2 times more contagious than the version of the virus previously found in Brazil, and 25% to 61% more capable of reinfecting people who had been infected with the previous strain, according to a study. released Tuesday.

With mass vaccination away across the region, countries like Brazil are at risk of becoming breeding grounds strong virus version that could make the current Covid-19 vaccine less effective, public health specialists warn.

A more prolonged pandemic could also devastate the economies of countries like Brazil, slow growth and widen already large piles of sovereign debt as governments make payments to the poor, economists say.

“We have a dramatic situation here – the health systems in many states in Brazil have collapsed and others will be damaged in the coming days,” said Eliseu Waldman, an epidemiologist at the University of São Paulo.

Health workers check arrivals at a field hospital in Manaus, Brazil, on Feb.11.


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Several doctors have reported a surge in younger patients on their Covid-19 wards, many in their 30s and 40s with no underlying health problems. In Peru, some doctors said patients became seriously ill sooner, just three or four days after first symptoms appeared, compared with an average of nine to 14 days last year.

“This virus behaves differently,” said Rosa Lopez, a doctor in the intensive care unit at Guillermo Almenara Irigoyen Lima Hospital. “It is very aggressive … the situation is very difficult, very dire.”

The Amazonian strain, P.1, emerged in the Brazilian city of Manaus late last year and quickly caught the attention of Brazilian and international scientists racing to map its distribution. The large number of variant mutations to the spike protein, which help the virus penetrate cells, is of particular concern.

“We are at the worst of times. I wouldn’t be surprised if P.1 were all over Brazil now, ”said Felipe Naveca, a researcher at the Oswaldo Cruz Foundation who has studied the new strain. He estimates that Brazil is already home to hundreds of new Covid-19 variants, even though P.1. is the most worrying so far, he said.

However, researchers are still confused as to why more young people are getting sick and whether P.1 is more deadly, or more contagious.

“The recent epidemic in Manaus has weighed on the city’s health care system, leading to inadequate access to medical care,” wrote study author P.1, led by Nuno Faria, a professor of viral evolution at the University of Oxford and Imperial College London. .

People wait to fill empty oxygen cylinders on the southern outskirts of Lima, Peru, on Feb.25.


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“We were therefore unable to determine whether the estimated increased relative risk of death was due to P.1 infection, pressure on the Manaus health care system, or both,” they wrote.

A study led by Mr Naveca released last week showed that in some cases the P.1 strain carried a viral load about 10 times higher than the initial version of the virus circulating in Brazil for most of the pandemic. But an international group of scientists led by Mr Faria concluded that it would not be possible to determine whether P.1 infection was associated with increased viral load until detailed clinical investigations were carried out.

Researchers in South Africa grapple with the same questions while studying Another new variant, B.1.351. Doctors there also reported increased hospitalizations and deaths for younger patients, but the researchers concluded that more younger people became seriously ill as more people became infected overall. The likelihood of younger people dying increased, they said, because hospitals were overwhelmed, not because the variant itself was more lethal.

Another possible explanation for the increase in younger patients is that the virus has spread through many of the elderly who have died, said Francisco Cardoso, an infectious disease specialist at Emílio Ribas hospital in São Paulo.

Latin America has been one of the world’s Covid-19 hotspots since the pandemic began, but in recent days doctors in Brazil have grown increasingly desperate, portraying horror scenes across the country. While the new strains are largely to blame, so is a lack of preparation and prevention by regional governments, said public health specialists.

Hospitals operate with ICU occupancy rates above 80% in nearly two-thirds of Brazilian states. After many patients suffocate in Manaus Earlier this year when the hospital ran out of oxygen, prosecutors were investigating reports from another Amazon city that intubated patients were tied to their beds after a sedative shortage.

In Peru, where the government has detected the P.1 strain, hospitals were quickly pushed out of capacity as infections spiked in January after one of the world’s worst outbreaks last year. Doctors are now choosing among dozens of patients when the ICU beds are open, while Chile is donating rescue oxygen amid an acute shortage.

The scene comes as the US, UK and Israel celebrate falling infection rates amid a mass vaccination campaign, evidence of a widening immunity gap between rich and poor countries. While more than 15% of people in the US have received a Covid-19 shot, Brazil has administered the vaccine to only 3% of the population. Peru and Colombia have vaccinated less than 1%.

If Latin America doesn’t find a way to speed up vaccination campaigns, other countries such as Colombia and Bolivia that have seen a slowdown in recent infections could also fall victim to the new variant, infectious disease specialists said.

The longer the disease is allowed to rot in countries like Brazil, the more likely it is that new variants will emerge that reduce the effectiveness of the Covid-19 vaccine, thus also becoming a threat to countries that have immunized their populations.

“Unless everyone in the world gets the vaccine immediately, none of us will be protected,” said Patricia Garcia, a former Peruvian health minister and epidemiologist. It will never stop.

Cesar Palacios, a 44-year-old pediatrician in the northern Peruvian city of Piura, lost his parents and younger sister to the disease earlier this year. She spent 10 days on a ventilator after she fell ill herself, her illness escalating rapidly as oxygen levels in her blood dropped to dangerous territory, at 86% just a day after her first symptoms. A few days later he was in the ICU.

“When you are going to be on a mechanical ventilator, you think, am I going to live? Am I going to die? “Said Dr. Palacios. “I have no other choice. I am very afraid. “

While Peru has imposed a curfew on Lima and other states with high infections, Brazilian cities such as São Paulo and its capital, Brasília, have imposed stricter restrictions over the past few days.

But many Brazilians break the rules, following directions from the country’s president. Right-wing leader Jair Bolsonaro has played down the disease and attacked state governors for imposing a lockdown, accusing them of destroying local businesses.

The military police in São Paulo raided about 50 companies over the weekend that refused to comply, including a group of 190 elderly Brazilians holding a clandestine party.

As a highly contagious variant of the coronavirus spreads around the world, scientists are racing to understand why this new version of the virus is spreading faster, and what this means for the vaccine effort. New research says the key may be spike protein, which gives the coronavirus its unmistakable shape. Illustration: Nick Collingwood / WSJ

Write to Samantha Pearson at [email protected] and Ryan Dube at [email protected]

Copyright © 2020 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7b1cdeb8

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Booking stock gains despite continued erosion of online travel activity | Instant News


Booking Holdings Inc.’s operations continued to struggle with the COVID-19 pandemic at the end of 2020, but held up better than analysts expected. Booking BKNG, + 3.57%, known as Priceline before changing its corporate name to one of its other online travel brands, said fourth-quarter losses on Wednesday of $ 165 million, or 4 .02 dollars per share, down from earnings of $ 27.75 per share. in the same quarter a year ago. Sales fell to $ 1.24 billion from $ 3.34 billion during the 2019 holiday season. After adjusting for some tax impacts and other costs, Booking recorded a loss of 57 cents per share, down compared to adjusted earnings of $ 23.30 per share a year ago. Analysts on average expected adjusted losses of $ 4.28 per share on sales of $ 1.2 billion, according to FactSet. Shares gained around 2% after hours of trading following the release of results. The travel industry came under fire during the COVID-19 pandemic and the decline worsened in the last quarter of the year, with the coronavirus causing more lockdowns. Chief Executive Officer Glenn Fogel issued a note of hope in a statement during Wednesday’s announcement. “The travel environment continued to be difficult during the fourth quarter of 2020 and through January 2021 as the number of COVID-19 cases remained very high and travel restrictions were reimposed in many. regions of the world, ”Fogel said. “However, in recent weeks we have started to see improvements in booking trends which we will continue to monitor.” Although Booking did not provide a forecast for the first quarter in Wednesday’s announcement, analysts expected any recovery to start further into 2021. “Given the likelihood of lockdowns extending as far as in March (notably in the UK) we expect a reset is needed for 1H: 21 Street forecasts (with our estimates) as intra-quarterly travel is muffled, although this should be to some extent within the expectations, ”Stifel analysts wrote in an online travel revenue snapshot earlier this month. “We believe the situation looks more favorable over a 12 to 18 month period for Booking, given the strong leverage effect on leisure travel, exposure to alternative accommodation and the ability to generate revenue.” Investors have been betting heavily on a possible turnaround, as Booking shares jumped over 27% last month and are now up over 36% last year, while the S&P 500 SPX index, +1, 14%, increased by 20.3%. Some of these gains appear to be linked to the initial public offering and early trading by Airbnb Inc. ABNB, + 6.72%, which sells full-residence accommodation instead of hotels – Booking and another rival, Expedia Group Inc. EXPE, + 1.93%, offer similar options in their brand portfolios. “A public assessment of Expedia’s alternative accommodation portfolio in the form of Airbnb seems to suggest a significant pricing error one way or the other” and “a similar argument can be made for Booking on a sum basis parts relating to Airbnb, ”Wedbush analysts wrote earlier this month, while improving Expedia’s stock and raising their reservation price target. Airbnb, which is worth more than Booking despite being considerably smaller, is expected to publish its results for the first time as a public company on Thursday afternoon. Airbnb stock, which sold for $ 68 when it went public in December, closed at more than $ 200 on Wednesday. .



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Airbnb’s first profits since its IPO could be an indicator for the travel industry in 2021 | Instant News


Airbnb Inc.’s business was decimated by the coronavirus pandemic, but quickly rebounded to the point that it had one of the biggest initial public offerings of 2020. Now is the time to find out what is expected. for 2021. Airbnb ABNB, -5.19% will report financial results for the first time since going public on Thursday afternoon, ending a blistering year for the company and a difficult year for the travel industry. So far, it appears that the online accommodation booking platform has been better positioned to deal with the pandemic than other companies in the travel industry, as travelers have finally sought out getaways near their homes where they could. avoid other people. Airbnb “has shown it to be more resilient to this particular shock of traveling,” said Tom White, analyst at DA Davidson. Airbnb reported third-quarter profit of $ 219 million, in part thanks to aggressive cost-cutting measures it implemented, on revenue of $ 1.34 billion – its second largest quarter never recorded. But an increase in COVID-19 cases in the fourth quarter led to further travel restrictions, which weighed on other companies in the industry, such as Expedia EXPE, -0.73%, and could also be reflected in Airbnb results – Analysts expect less than $ 750 million in fourth quarter revenue. The prospects offered by Airbnb could be greater for Airbnb and the travel industry. Airbnb released a report at the end of January in which it cited the results of its own survey as saying, “A majority of Americans (54%) have already booked, are currently planning to travel, or are planning to travel in 2021.” It remains to be seen whether travelers will still be pitted against Airbnb’s main competition: hotels. “Unless there is a structural change in traveler behavior, the change in preference is likely to be gradual, especially when hotels are back on a level playing field,” KeyBanc Capital Markets’ Justin Patterson wrote in a recent note. What to expect Profits: Analysts polled by FactSet are forecasting an average loss of $ 8.41 per share, largely thanks to the equity compensation costs of Airbnb’s IPO. Estimize, which brings together estimates from analysts, hedge fund managers, executives and more, expects a loss of $ 6.09 per share on average. Revenue: Analysts are expecting an average of $ 739.4 million in revenue, according to FactSet. The estimate is $ 775.9 million. Stock movement: Airbnb shares gained 35% during their period in public markets, while the S&P 500 SPX index, -0.49%, rose 6.5% during this period. a quarter-over-quarter slowdown in the fourth quarter in Europe and “lingering weakness” in the first quarter. But they said they believed Airbnb would withstand a downturn better than other online travel companies “given its focus on alternative accommodation inventory.” Growth: Airbnb continued to outperform hotels and OTAs in December year over year, KeyBanc analysts wrote in a note, which also said Airbnb and its smaller rival Vrbo had experienced positive growth year-over-year spending in January. The CFRA said in a note that it expects a strong rebound in bookings in 2021, including monthly bookings exceeding previous peak levels by the end of the summer. Regulatory risks: Airbnb faces bans and restrictions on stays or listings in different regions of the world. In his home country, he may also be affected by efforts to amend or reject section 230 of the Communications Decency Act, which, among other things, protects him and other companies based in line, of any responsibility for the words and actions of their users. Sucharita Kodali, an analyst at Forrester, said that if Section 230 “was canceled, it would dramatically change all markets.” Without Section 230, she said Airbnb would have “a lot more than it needs to master,” as it could potentially face lawsuits for rental clauses, property damage and violence. Of 29 analysts polled by FactSet, 10 have a buy rating on Airbnb stock, while 16 have a hold, two say sell and one considers the stock’s overweighting. The average price target was $ 164.65 on Monday, when the stock closed at $ 195.34. .



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