Tag Archives: Orthopedics

US skier Tommy Ford continues to recover from an accident at his home in Bend Sports | Instant News


Tommy Ford doesn’t remember the terrible accident that ended the World Cup ski season on January 9.

He remembers waking up in a Bern hospital, Switzerland, and studying injuries to his head, right knee and left wrist.

“I don’t remember the accident at all or the next hour,” Ford said in an interview with The Bulletin last week. “I don’t remember the helicopter ride I looked like going through.”

Ford, who can get around on crutches but can’t stand for long, has been returning home in Bend over the past few weeks, getting help and support from his parents and older brother.

“You learn what support systems are, or become more aware of them, when you are less capable,” Ford said.

31-year-old Ford – a two-time Olympic athlete born and raised in Bend – is in the middle of the 2020-21 season banner, posting four World Cup top 10 results in the giant slalom, including taking the podium in Santa Caterina, Italy.

He has qualified for the world alpine skiing championships, currently being performed in Cortina d’Ampezzo, Italy.

One of the top-ranked riders at the World Cup giant slalom race in Adelboden, Switzerland, Ford crashed three gates from the finish line after spreading into rough snow beside the track, according to the Associated Press.

His skin touched and he fell forward, sliding first down the hill on his neck and left shoulder.

Ford hit a worker on the side of the track before stopping by the safety net beside the finish.

He initially lay still with his face facing the snow despite immediately regaining his senses and talking to the medical staff, whom he doesn’t remember.

A helicopter lands in the field 20 minutes later to transport Ford to Bern.

Ford’s long-time girlfriend Laurenne Ross, also a World Cup skier and two-time Olympian from Bend, is watching Ford’s race on television as she prepares to race her first World Cup in two years after overcoming multiple knee injuries.

“It totally baffles me,” Ross wrote in an email last week from Cortina d’Ampezzo, where she finished 26th on Saturday in a world championship decline. “Obviously I am very concerned about his head injury, because obviously he is passed out. I’m usually pretty comfortable watching Tommy ski – he’s a solid, smooth skier – but he’s definitely over the top, and pushes the skis… and sometimes you crash when you’re skiing over the edge. Needless to say, I am very sad for him. “

After several days in Bern following the accident, Ford traveled to Vail, Colorado, where doctors at the Steadman Philippon Research Institute repaired torn ligaments in his knee and wrist. He is scheduled to return to Vail later this month for additional surgery on his knee. Ford said he tore two ligaments in his right knee and also fractured a plateau and tibial meniscus.

He also continues to recover from the concussion he suffered.

“I don’t have a headache or anything, but I have limited capacity for stimulation,” he said.

Ford said he was happy to be at his parents’ home in Bend, where he was getting plenty of sleep and rest, and was “starting to recover.” He wears a detachable splint on his left wrist and his right knee is in a brace, which he can remove as often as possible.

He added that it was too early to discuss a time frame for a possible return to ski racing or to bid for his third US Olympic Team. The 2022 Winter Olympics in Beijing are only one year away.

“There is no time frame that is overly detailed at the moment because I will have to have another operation,” Ford said. “I have to bear more weight in March. That’s all I really know. It’s still very early days. I haven’t gotten too far with the emotional side of things and all of that. “

Although Ross continues to race in Europe and Ford has returned home to Bend, the two are able to discuss Ford’s injury and his approach to rehabilitation. Ross, 32, has had 10 surgeries during his skiing career, three of which were major knee operations.

“Unfortunately Laurenne has a lot of experience with knee injuries, and she’s been very helpful with some advice,” said Ford. “I just don’t want to burden him because he also tries to perform at a high level and you don’t want to talk about injuries all the time. But he’s very helpful. He’s really entertaining. “

Ross said he was sure Ford would take the time and get back into the snow when he was “really ready.”

“Hopefully it will be race time next season, but we’ll just have to wait and see,” said Ross. “I’m here for him, every step of the way, whatever it is. I do have the insights I have shared, but everyone is very different when it comes to healing and processing. So I just try to support Tommy in whatever way he needs me to be there, in whatever way he wants to approach his recovery. It’s been the ride, and although I can offer advice, I know we are very different people, very different skiers, and often have different perspectives on injury and recovery. “

Ross added that the most important thing on which Ford is currently focused is “rest, recovery and reflection”.

“It’s important to consider if you want to get another injury (like the one he’s recovering from now), because that’s always the chance you take when you push out the starting gate in a ski race,” said Ross. “But first, he needs to focus on healing.”

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Completeness and capture rate of publicly funded arthroplasty procedures at Joint Registration of New Zealand | Instant News


Background: Registry-based studies are becoming more common because of the availability of large study cohorts. However, the validity of the findings depends on the completeness of the registry. This study aims to validate the New Zealand Joint Registry (NZJR) catch rate by matching procedures that have been recorded separately through clinical coding by the New Zealand Government’s National Surgical Site Infection Improvement Program (SSIIP).

Method: The National Health Index, a unique identification code for all patients, was combined with the arthroplasty procedure performed (primary total knee arthroplasty (TKA), primary total hip arthroplasty (THA), revised TKA or revised THA) and side surgery. Publicly funded procedures recorded in the NZJR are matched with procedures recorded by SSIIP on a record by record basis. This identifies the total number of arthroplasty procedures performed in New Zealand, which is used as the denominator value to calculate the arrest rate for the NZJR procedure.

Result: Between 2013 and 2018, 24,556 SD TKA, 28,970 THA primary, 2107 revised TKA and 4263 revised THA procedures were recorded by both datasets. The NZJR recorded 95.5% of primary TKA procedures, 96.3% of primary THA procedures, 97.1% of revised foreign workers procedures, and 95.2% of revised THA procedures.

Conclusion: The NZJR records> 95% of arthroplasty procedures are publicly funded. In contrast, there were inaccuracies in the clinical coding by the hospital, particularly with the revised procedure, suggesting the benefit of the arthroplasty registry. However, the data recorded by the infection surveillance program can complement the arthroplasty registry data to strengthen the quality of the study.

Keywords: arthroplasty; clinical coding; joint replacement; registrant; surgical wound infection.

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Tiny balls of minerals better means for prospective mRNA therapy | Instant News


University of Wisconsin-Madison researchers have developed safer and more effective way to deliver promising new treatment for cancer and liver diseases and for vaccination, including COVID-19 vaccine from modern therapy, which was published in clinical trials with people.

The technology is based on the introduction in cells pieces of carefully designed RNA (mRNA), a strip of genetic material of human cells usually decode human DNA, to make beneficial proteins and to go about their business. Problems delivering RNAi safely and undamaged without breaking the immune system inhibit mRNA therapy, but UW-Madison researchers make little balls of minerals that seems to do the trick on mice.

These microparticles have pores on their surface, which are in the nanometer scale that will allow them to lift and carry molecules, such as proteins or RNA. They mimic something seen often in archaeology, when we find intact protein or DNA in the sample is bone or eggshell from thousands of years ago. The mineral components help to stabilize these molecules for all this time.”

William Murphy, Professor of biomedical engineering and Orthopaedics, UW-Madison

Murphy and UW-Madison collaborators used mineral-coated microparticles (ILMC), which in the diameter from 5 to 10 µm, the size of a man … in a series of experiments to deliver RNA into cells around the wound in diabetic mice. Wounds healed faster in MCM-treated mice, and cells in adjacent experiments have shown a much more efficient pickup of mRNA molecules are compared with other delivery methods.

The researchers described their findings today in the journal Science Progress.

In a healthy cell, DNA is transcribed into mRNA and the mRNA serves as the instructions the cell uses to produce proteins. Strip mRNA created in the laboratory can be replaced in the process to tell the cell to do something new. If something is of a certain type of antigen molecule that alerts the immune system to the presence potentially dangerous virus mRNA did the work of the vaccine.

At UW-Madison researchers encoded an mRNA with instructions directing the cells ribosomes to pump out the growth factor, a protein that encourages the healing process, which otherwise is slow to unfold or absent in diabetic mice (and many serious patients with diabetes).

mRNA short-lived, although in the body, so to deliver enough cells usually means of the introduction of large and frequent doses, in which mRNA strands is carried out containers made of molecules called cationic polymers.

“Often the cationic component is non-toxic. The more mRNA you put, the more therapeutic benefit you will receive, but the greater the likelihood that you’re going to see a toxic effect. So, it is a compromise,” says Murphy. What we found when we ship out of the ILMC, we do not see toxicity. And because the supply mkm protects mRNA from degradation, you can get more mRNA where you want it, to reduce toxic effects.”

The new study also paired mRNA with the immune system inhibiting protein, to make sure that the target cell did not take mRNA as foreign bodies and destroy or remove it.

Successful delivery of mRNA, as a rule, keeps the cells working on new instructions for about 24 hours, and molecules that they produce to disperse throughout the body. This is sufficient for vaccines and antigens they produce. To maintain the long processes of growing replacement tissue to repair the skin or organs, proteins and growth factors produced by cells want to hang around here much longer.

“What we saw with mcms is once the cells absorb the mRNA and start to take protein is that the protein will bind right back to MICRON particles,” says Murphy. “Then he was released within weeks. We basically take something that would normally last maybe hours or even a day, and we do it in the past for a long time.”

Because MCMS are large enough that they do not get into the bloodstream and disappear, they stay where they need to keep releasing useful therapy. In mice that therapeutic activity to continue for more than 20 days.

“They are made of minerals similar to tooth enamel and bone, but designed to be absorbed into the body when they are not useful anymore,” says Murphy, whose work is supported by the Agency for environmental protection, the National institutes of health and the national science Foundation, and donations from University of Wisconsin-Madison alum Michael and Mary sue Shannon.

“We can control their lives, adjusting as they are made so they dissolve harmlessly, when we want.”

The technology underlying the microparticles were patented by research Fund of the graduates of the University of Wisconsin and is licensed to Dianomi therapy in the company Murphy co-founder.

The researchers are now working on growing bone and cartilage tissue and restore injury to the spinal cord with the mRNA made by the ILMC.

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