Tag Archives: Research

Research identifies failures in hotel-based COVID-19 quarantines in Australia and New Zealand | Instant News


Australia and New Zealand are among the countries that have succeeded in suppressing the transmission of the coronavirus disease (COVID-19). Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the infection has now infected more than 111 million people worldwide.

In an effort to reduce transmission of the virus, hotel-based quarantine as part of the COVID-19 border control effort is implemented. Arriving tourists must undergo a 14-day quarantine period at the hotel facilities to ensure they do not carry the virus.

Although these countries managed to reduce the number of cases, researchers at the Department of Public Health, Otago Wellington University, New Zealand, and the Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia, wanted to measure the risk of failure when using hotel-based quarantine for COVID. -19.

Researchers found a significant risk of failure with hotel quarantines in Australia and New Zealand. The two countries collectively have 16 COVID-19 identified failures from hotel-based quarantine through January 31, 2021. The two countries also have a higher proportion of infected travelers, threatening the status of both countries in eliminating the disease.

The team recommends that immediate improvements to quarantine need to be implemented.

Hotel-based quarantine

Many countries carry out hotel-based quarantine for incoming residents from other countries and travelers. New Zealand and Australia have succeeded in eliminating communities transmission of COVID-19. Although outbreaks occasionally occur, they are controllable.

In the hotel quarantine, passengers and travelers are required to undergo a quarantine period of 14 days at hotel facilities approved by the government. After a 14-day quarantine combined with a negative polymerase chain reaction (PCR) test for SARS-CoV-2, travelers are free to leave.

Changing hotels for quarantine purposes has the advantage of using resources that shouldn’t be used during a pandemic. There are international travel restrictions for both countries, so there are guest restrictions at hotels.

However, the hotel quarantine also has drawbacks. These include having to live in shared spaces, leakage of viruses from health facility personnel, and lack of proper ventilation.

Learning

Studies published on preprint servers medRxiv*, looked to determine whether hotel-based isolation facilities were effective and feasible in reducing the spread of SARS-CoV-2.

To arrive at the study findings, researchers searched official websites in both countries and for eight regions in Australia. In this way, they can identify outbreaks and border control failures related to hotel quarantines.

The team identified failures using a common denominator, such as the estimated number of travelers passing through the facility and the number of SARS-CoV-2 positive people passing through the facility simultaneously.

What they found

Based on all testing, before 31 January 2021, Australia had seven failures, with one causing 800 deaths. Meanwhile, in New Zealand, there were nine failures, one leading to three deaths and lockdowns.

The team estimated that the overall risk for the two countries combined was one failure per 20,702 travelers. The researchers used two denominators – an estimate of the number of births per day and the number of COVID-19 cases.

“There appears to be a marked risk of failure with the use of hotel quarantines in these two countries. The large variation in infection control practices suggests opportunities for risk reduction,” the investigators concluded.

“Another risk reduction practice would be to use better facilities in rural locations as there is less risk of close contact in CBD hotels and spread within buildings from poor ventilation systems,” the team added.

The investigators concluded that to substantially reduce the risk of SARS-CoV-2 entry from quarantine, the most obvious course of action would be to reduce arrivals or even delay arrivals from sites of high infection.

The COVID-19 pandemic has hit many countries, such as the US, UK, South Africa, India and Brazil. The US has the highest number of infections reported to date, with 28.18 million cases. Meanwhile, other countries reported skyrocketing cases, including India, with more than 11 million cases and Brazil, with more than 10 million.

* Important Notice

medRxiv publishes preliminary scientific reports that are not peer reviewed and, therefore, should not be construed as conclusions, guidelines for health-related clinical / behavioral practice, or are treated as defined information.

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Apple users could spend more on non-gaming mobile apps by 2024 – report | Instant News


FILE PHOTO: Apple Inc logo seen hanging at the entrance of an Apple store on 5th Avenue in Manhattan, New York, USA, October 16, 2019. REUTERS / Mike Segar

(Reuters) – Apple Inc customers will likely spend more money on non-gaming mobile apps by 2024, data analytics firm SensorTower said on Monday, as the lockdown lifestyle results in users looking more than just games to apps that help with service delivery. more important.

Downloads of business, education, health and wellness apps have seen a sharp spike due to stay-at-home acts during the health crisis.

During the early days of the pandemic, users spent even more money on mobile games on the App Store. But as the lockdown extended, improving work-life and modes of communication, their attention turned to photo and video sharing, dating, video conferencing and instant messaging apps.

Shares of companies such as Zoom Video Communications Inc and Match Group as well as other household companies surged last year.

SensorTower says consumer spending on mobile apps will reach $ 270 billion in the next five years globally, more than tripling when compared to 2020.

Apple customers will spend more than their Android counterparts with the App Store which is expected to generate $ 185 billion in global revenue, the data analysis firm said.

Gaming revenue will continue to take up a relatively higher share of the Google Play store than it does on the App Store, with a projected 71% share of games in 2025 compared to 42% on the App Store, data shows.

The data analytics firm expects Europe to become a key market over the next five years, with revenue growth on the continent likely to outpace growth in Asia and North America.

Downloads in Europe are expected to grow to 36.9 billion by 2025, compared with 28.4 billion in 2020, while revenue growth is expected to more than double to $ 42 billion in the next five years.

Reporting by Eva Mathews and Subrat Patnaik in Bengaluru; Edited by Arun Koyyur

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Apple users could spend more on non-gaming mobile apps by 2024 – report | Instant News


FILE PHOTO: Apple Inc logo seen hanging at the entrance of an Apple store on 5th Avenue in Manhattan, New York, USA, October 16, 2019. REUTERS / Mike Segar

(Reuters) – Apple Inc customers will likely spend more money on non-gaming mobile apps by 2024, data analytics firm SensorTower said on Monday, as the lockdown lifestyle results in users looking more than just games to apps that help with service delivery. more important.

Downloads of business, education, health and wellness apps have seen a sharp spike due to stay-at-home acts during the health crisis.

During the early days of the pandemic, users spent even more money on mobile games on the App Store. But as the lockdown extended, improving work-life and modes of communication, their attention turned to photo and video sharing, dating, video conferencing and instant messaging apps.

Shares of companies such as Zoom Video Communications Inc and Match Group as well as other household companies surged last year.

SensorTower says consumer spending on mobile apps will reach $ 270 billion in the next five years globally, more than tripling when compared to 2020.

Apple customers will spend more than their Android counterparts with the App Store which is expected to generate $ 185 billion in global revenue, the data analysis firm said.

Gaming revenue will continue to take up a relatively higher share of the Google Play store than it does on the App Store, with a projected 71% share of games in 2025 compared to 42% on the App Store, data shows.

The data analytics firm expects Europe to become a key market over the next five years, with revenue growth on the continent likely to outpace growth in Asia and North America.

Downloads in Europe are expected to grow to 36.9 billion by 2025, compared with 28.4 billion in 2020, while revenue growth is expected to more than double to $ 42 billion in the next five years.

Reporting by Eva Mathews and Subrat Patnaik in Bengaluru; Edited by Arun Koyyur

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Deaths from anaphylaxis have halved even though the number of patients in hospital is increasing: Study | Instant News


A study published in the journal BMJ describes the death rate from food-induced anaphylaxis that has halved despite the greatly increased hospital admission rates in the UK due to this life-threatening allergic reaction disease.

Food allergies are the most common cause of a potentially life-threatening allergic reaction, known as anaphylaxis. Substantial increases in hospital admissions due to food anaphylaxis have been reported globally, but it is unclear whether this trend continues, and if so, whether it has led to an increase in fatal reactions.

To explore this further, researchers from Imperial College London’s National Heart & Lung Institute began describing trends in hospital admission times for food anaphylaxis in the UK over the past 20 years.

They studied data between 1998 and 2018, measured trends in time, age, and sex distribution for anaphylactic admissions due to food and non-food triggers, and then compared them to reported deaths.

Between 1998 and 2018, 101,891 people were hospitalized for anaphylaxis. Of these, 30,700 (30%) were coded for food triggers.

Acceptance of food anaphylaxis increased from 1.23 to 4.04 per 100,000 population per year (from 1998 to 2018), an annual increase of 5.7%.

The largest increase in hospital admissions was seen for children under 15 years, with an increase from 2.1 to 9.2 admissions per 100,000 population per year (an annual increase of 6.6%, compared to 5.9% for people aged 15-59 years and 2.1% in those aged 60 years and over).

Over a 20 year period, 152 deaths were identified in which the fatal event may have been due to food-induced anaphylaxis.

The case-fatality rate (number of deaths as a proportion of admissions) decreased from 0.7% to 0.19% for confirmed fatal food anaphylaxis and to 0.3% for food anaphylaxis that was suspected to be fatal.

At least 86 (46%) of all deaths between 1992-2018 were triggered by peanuts or tree nuts, while cow’s milk was responsible for 17 (26%) deaths in school-age children.

The data also show that over the same time period, prescriptions for adrenaline autoinjectors increased 336% – an increase of 11% per year.

The investigators say that improvements in the introduction and management of anaphylaxis may partially explain the reduction in case mortality despite increasing hospital admissions for anaphylaxis.

There is no evidence to suggest that the clinical criteria used to diagnose anaphylaxis have changed in the UK over the study period, they added. Although the National Institute for Health and Care Excellence (NICE) introduced national guidelines in 2011, which could result in an increase in the number of hospitalized patients, year-on-year increases have continued since then.

The authors acknowledged some of the study limitations, such as the possibility of some miscoded or misdiagnosed anaphylaxis cases, and they were unable to include anaphylaxis cases seen in an emergency department that did not require hospital admission.

However, they do use national data sets in the context of the UK health system, which provides an opportunity to draw strong conclusions compared to other countries.

Thus, the researchers conclude: “Cow’s milk is increasingly being identified as an allergen cause for fatal food reactions, and is now the most common cause of fatal anaphylaxis in children. More education is needed to highlight the specific risks that cow’s milk poses to people. -people who are allergic to raise awareness among the food business. “

They added: “Further work is needed to assess evidence of age-related susceptibility to severe anaphylaxis in young adults, thereby increasing our ability to stratify the risk of patients with food allergies and to reduce the risk of fatal outcomes.”

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This story has been published from wire agent bait without modification to the text.

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Q&A: How Can Doctors Reduce the Risk in a Pregnant Woman with Diabetes? | HCPLive | Instant News


Women with diabetes have a higher risk of several diseases complications if they are pregnant, including preterm birth, low or high birth weight, stillbirth, and congenital abnormalities.

Existing evidence has shown that lifestyle interventions can help reduce complications and improve outcomes in diabetes patients, but whether pregnancy-related complications can be reversed is poorly understood. The problem is very troublesome in terms of type 2 diabetes (T2D), which is a growing problem in many parts of the world.

Helen R. Murphy, MD, of the University of East Anglia, and colleagues, recently completed a Population-based cohort study over 5 years more than 15,000 pregnancies in Great Britain, Wales and the Isle of Man completed between 2014-2018 and were included in the UK’s National Pregnancy Database for Diabetes.

HCPLive asked Murphy to discuss what his findings were and what they had to say about the benefits of the intervention.

HCPLive: Diabetes in pregnancy has been studied before, but your research is well known for its size and scope. Half of the pregnancies occur in women with type 1 diabetes (T1D) and half in women with type 2 diabetes. What are the implications of having such a large study population?

Murphy: Yes, by far the largest contemporary study in diabetes pregnancy. Historically, there have been several studies of 5,000 pregnancies in women with type 1 diabetes but usually over a time period of 15 years (eg Sweden 1991-2003), so at the time of publication this was outdated. Our data are contemporary and highly relevant to current clinical practice. In particular, none of the previous studies included large numbers of women with type 2 diabetes, which is a growing concern among women of childbearing age, especially those from disadvantaged ethnic groups or blacks and minorities.

Your study identifies maternal glycemia and body mass index (BMI) as the main modifiable risk factors in pregnant women with diabetes. How do doctors advise women with diabetes who are planning to become pregnant?

There is an important impact of the mother’s pre-pregnancy BMI on glucose levels during pregnancy, so I think encouraging women to optimize their dietary intake and enter a healthy pregnancy as close as possible before pregnancy is a very important component of pregnancy planning. both on T1 and T2D.

Should the emphasis be on making interventions before pregnancy, or can meaningful changes be made during pregnancy too?

During pregnancy, efforts can be made to limit excessive pregnancy weight gain, but it is too late to ‘undo’ the effects of BMI of being overweight / obese in early pregnancy.

Is there anything in particular that surprises you?

I was shocked about the impact of maternal weight on T1D. We already know that maternal glycemia is important, but I did not realize that early BMI has a strong influence on the glucose level of the mother during pregnancy and also on pregnancy outcome.

In T2D, I expected maternal obesity to have an impact, but was surprised by the impact of maternal glucose – which was much stronger than expected.

What is the main key for doctors?

The good news is that maternal glucose is relatively easy to change in T2D pregnancy, so the take-home message for me is to focus more on pre-pregnancy weight in T1D and on maternal glucose levels during pregnancy in T2D pregnancies.

Another key message is that changes are needed in all clinics to intensify glycemic management. In T1D that means recognition [continuous glucose management] for all pregnant women in all maternity clinics, and for T2D we need to be serious about pre-pregnancy diabetes prevention and weight management programs.

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