Lahore:the preliminary results of the largest drug trial Covid-19 “Pakistan randomized and observational trial to assess syndrome treatment (protect)”, not only ensuring the safety of hydroxychloroquine, a drug commonly used to treat malaria, from the point of view of mortality but also demonstrated a significant rise in rates Covid-19 patients when used in combination with two other drugs – azithromycin and oseltamivir.
The results were announced here at the University of health Sciences (UHS sales), on Monday, in a ceremony headed by Governor Punjab Chaudhry Muhammad Sarwar, and by the regional Minister for higher education, Raja Yassir Humayun, rectors of medical schools, researchers, and educators.
Releasing the results of the research Vice-Chancellor of the UHS sales, Prof Javed Akram, who is also the chief investigator explained that she was involved in the evaluation of hydroxychloroquine alone and in various combinations of drugs in the treatment of the crown.
“This multicenter, adaptive, randomized controlled drug trial aimed at newly diagnosed patients,” he said. He said that the study showed that COVID-19 patients treated with three drugs combined the rate of recovery of 86 per cent.
For the occasion, paying rich Tribute to health workers, the Governor noted that the nation will never forget the courage and bravery with which health workers fought against the crown.
“The memorial wall is erected in Governor house in recognition of his services to health workers who will carry the names of all the veterans,” he added. The Governor urged the rectors of medical universities Supermen. He added that the strength and vitality of this nation was equal in the world. He said while it is encouraging to see cases of the virus decreases, the markets are now cattle, Eidul Azha and Muharram, and is a serious challenge in relation to controlling the spread of infection again.
“If these problems are overcome, we can overcome the crown,” the Governor claimed. UHS sales VC Prof Javed Akram informed the participants that the experimental drug was launched on 30 April, after approval from the regulatory authority of drugs of Pakistan (DRAP) and the National bioethics Committee (NKB). He said that the study included 12 centres, including 10 high schools from eight cities. The study included crown-positive patients older than 18 years, who were divided into eight groups. Patients included in the study were 60 percent men and 40 percent women. Three drugs were given to seven groups, each with 60 to 65 patients, alone and in various combinations, while one control group was not given.
Prof Javed Akram said that the pace of recovery from a combination of three drugs was the highest at 86 percent. The second highest recovery rate was 75 percent of the Azithromycin. The overall level of recovery of patients who were given medicines amounted to 73.1%, and the rate of recovery without drugs was 67 percent. In addition, 27 percent of patients remained in the Crown positive, even two weeks after taking the drug. In patients who were not given any drugs, 33 percent remained in the Crown positive, even after two weeks.
Vice Chancellor UHS sales added that the pace of recovery in the first week of the study was 33.5%, and in the second week it increased to 72.2 percent. Initially, a test PCR was used as the basis for research. He noted that were recorded during the study a total of four deaths. Occurred three deaths in the groups receiving one medicine, while one death occurred in the group treated with the combination of hydroxychloroquine and Azithromycin.
He said that studies are still ongoing and will require about 9500 patients after. Prof Javed Akram said that Rs30 million had been spent on research so far, the University has collected from its own funds and through donations.
King Edward medical University VC, Prof Gondal Khalid Masood in his speech said that if standard operating procedures were implemented on Eidul Azha, the crown will be under control by September. Provincial Minister for higher education, Raja Yassir Humayun said that medical institutions can play an important role in scientific research. Pakistani doctors around the world. He praised the role of the UHS sales in research and noted that the research results were encouraging.
Prof Aamer Zaman Khan, Professor Aziz-ur-Rehman, Dr. Shehla Javed Akram, Prof Maryam Nawaz Tarar, justice (R) Tassaduq Hussain Jilani, Abrar-ul-Haq, Prof Mahmood Ayaz, Prof Asad Aslam, Dr. Somia Iqtadar, Dr. Farah Khalid, Professor Zafar Gil, Professor Hanif Nagra, Muhammad Shehzad, Dr. Allah rakha, buy Latif, Faisal Amin and Dr. Shah Nur was present. In the end, the Governor of Punjab Chaudhry Sarwar distributed shields among the participants.